RA is a chronic inflammatory condition leading to irreversible destruction and deformation of synovial joints. RA patients were found more prone to develop CVD as compared to normal individuals. So, the present study was designed to evaluate the various risk factors of CVD in RA patients from North India. Furthermore, the effects of obesity were also assessed on these studied parameters. The present study recruited 178 RA patients and 178 unrelated age, gender and ethnicity matched controls. Standard anthropometric measurements including weight, height, hip circumference and waist circumference were performed on each individual using standard anthropometric methodology. Body mass index (BMI), Waist hip ratio (WHR) and waist stature ratio (WSR) were calculated from the given data. Blood pressure was measured with a standard mercury sphygmomanometer. Mean arterial pressure (MAP) and pulse pressure (PP) were calculated using standard formula. Different lipid profile biomarkers and C-reactive protein (CRP) were quantified using standard reagents and kits. Lipid peroxidation was determined by quantitative analysis of serum malondialdehyde (MDA) by standard protocol. Data were analyzed using suitable statistical analysis. Present study indicated high prevalence of obesity, hypertension, inflammation, lipid peroxidation in RA patients in comparison to controls. Furthermore, obese RA patients were found to have significantly high atherogenic indices, CRP and MDA as compared to obese controls.