Pregnancy loss is influenced by various factors, out of which blood group incompatibility of parents could be a significant cause of abortion or any intrauterine fetal loss. Various incompatible combinations of parents blood group have already been identified in such marriages, frequency of spontaneous abortions have been found more and certain combinations found less chance of abortions. The present investigation seems more significant. Standard methods and techniques were adopted for collection of data and blood samples. A total number of 202 couples selected randomly were approached to get information about the reproductive life. The main aim of the present study is to establish a relationship between ABO incompatibility and fetal wastage among the Hill Korwas of Jashpur district of Chhattisgarh. Total pregnancy wastage among the Hill Korwa women have been observed to be 20.02%. Among incompatible mating the percentage of fetal wastage is higher at 26.62, as compared to compatible 14.28%. The percentage and frequency of abortion, prenatal deaths and still births are also higher in incompatible mating