Alteration of the dermatoglyphic traits served as one of the major criteria for understanding the human neurodevelopmental disorders and have already been well documented globally. The present study being the first attempt from India reports the palmar dermatoglyphics variability in terms of relationship of atd angle among the Autistic patients. To achieve the purpose, bilateral palm prints of 100 (67 males and 33 females) clinically diagnosed Autistic patients (DSM-IV-TR) from Bengalee Hindu Caste population of West Bengal, India. In addition to that, bilateral palm prints of 100 (55 males and 45 females) apparently healthy individuals without any family history of Autism were collected from the same area and population and treated as controls. All the prints were obtained following standard method and classified according to the standard procedures. The result demonstrated a significantly (p<0.05) higher atd angle among the Autistic patients than that of the controls. Thus the present study envisaged that the significantly (p<0.05) higher atd angle among the Autistic patients might be taken as one of the additional criteria for the early prognosis of Autism among the Bengalee Hindu caste population of West
Bengal, India.